Publikationen AK Frahm
Schriftenverzeichnis / Publications
2009-2000
Cytotoxic Properties of Root Extract and Fruit Juice of Trichosanthes cucumerina
Sumonthip Kongtun, Weena Jiratchariyakul, Tanawan Kummalue, Peerapan Tanariya,
Somyos Kunnachak, A.W. Frahm
Planta Med (2009) 75, 839-842
Phytochemical Investigation of Perovskia abrotanoides
S Khaliq, F.-J. Volk, A.W. Frahm
Planta Medica (2007) 73, 77-83
Cyclic Glutamic Acid Derivatives
Udo Meyer, Philippe Bisel, and August Wilhelm Frahm
Chirality (2006) 18, 383-394
Immunomodulatory Effect and Quantitation of a Cytotoxic Glycosphingolipid
from Murdannia loriformis
Weena Jiratchariyakul, Molvibha Vongsakul, Leena Sunthornsuk,Primchanien Moongkarndi, Ammararat Narintorn, Aimon Somanabandhu, Hikaru Okabe,
A.W. Frahm
J Nat Med (2006) 60, 210-216
A MEKC method for monitoring Mycophenolic Acid in serum of transplant recipients
L. Suntornsuk, Th. Meyer, A. Lindgren, A.W. Frahm
Pharmazie (2005) 60, 115-119
Rigid Non Proteinogenic Cyclic Amino Acids as Ligands for Glutamate Receptors:
The trans-tris-Homo-Glutamic Acids
Udo Meyer, Philippe Bisel, Hans Bräuner-Osborne, Ulf Madsen, Georg Höfner,
Klaus Th. Wanner and August Wilhelm Frahm
Chirality (2005) 17, 99-107
Structure-Activity Relationships of Novel P2 Receptor Antagonists Structurally Related to Reactive blue 2
M.Glänzel, R. Bültmann, K. Starke, A.W. Frahm
J. Eur.Med. Chem (2005) 40, 1262-1276
Asymmetric Strecker Synthesis of Enantiopure 2,4‑Ethanothreonines
U. Meyer, E. Breitling, P. Bisel, and A.W. Frahm
Tetrahedron Asymmetry (2004) 15, 2029-2037
Conformational Analysis of the Biflavanoid GB2 and a Polyhydroxylated Flavanone–chromone of Cratoxylum neriifolium
V. Kumar, V. Brecht, A.W. Frahm
Planta Medica (2004) 70, 646-651
Stereoselective Synthesis of ( 1R,2S )- and ( 1S,2R )-1-amino-cis-3-azabicyclo[4.4.0]decan-2,4-dione hydrochlorides : Bicyclic Glutamic Acid Derivatives
Ph. Bisel, K.P.Fondekar, F-J. Volk, A.W.Frahm
Tetrahedron (2004) 60, 10541-10545
Cyclobutane Amino Acids (CBAAs):
Asymmetric Strecker Synthesis of Enantiopure Cis- and Trans-2,4-Methanovalines
F.-J. Volk, M. Wagner, A.W. Frahm
Tetrahedron Asymmetry (2003) 14, 497-502
Constitutional Isomers of Reactive Blue 2 – selective P2Y-Receptor Antagonists?
M. Glänzel, R. Bültmann, K. Starke and A.W. Frahm
Eur. J. Med. Chem. (2003) 38, 303-312
Members of the Acid Blue 129 family as potent and selective P2Y-Receptor
Antagonists
M. Glänzel, R. Bültmann, K. Starke and A.W. Frahm
Drug Development Research (DDR) (2003) 59, 64-71
Comparison of three chiral stationary phases with respekt to their enantio-
and diastereoselectivity for cyclic ß-substituted a-amino acids
M. Schlauch, O. Kos, A. W. Frahm
J. of Pharm. and Biomed. Analysis (2002) 27, 409 - 419
Separation and first Structure Elucidation of Cremophor EL-components by hyphenated Capillary Electrophoresis and DE-MALDI-TOF-Mass Spectroscopy
Th. Meyer, D. Waidelich, A.W. Frahm
Electrophoresis (2002) 23, 1053 – 1062
Enantioselective determination of (R)- and (S)-sotalol in human plasma by on-line coupling of a restricted-access material precolumn to a cellobiohydrolase I-based chiral stationary phase
M. Schlauch, K. Fulde, A.W. Frahm
Journal of Chromatography B (2002) 775, 197 – 207
Polyoxyethylene-D9,11-didehydrostearate and glycerolpolyoxyethylene-
D9,11-didehydrostearate: two new components of the non-ionic emulsifier
Cremophor® EL
Th. Meyer, D. Waidelich, A.W. Frahm
J.of Pharm and Biomed Analysis (2002) 30, 263-271
Carbocyclic a,b-Diamino Acids: Asymmetric Strecker Synthesis of Stereomeric
1,2-Diaminocyclohexanecarboxylic Acids
K.P.Pai Fondekar, F.-J. Volk, S.M. Khaliq-uz-Zaman, P. Bisel, A.W. Frahm
Tetrahedron Asymmetry (2002) 13, 2241-2249
Expeditious Synthesis and chromatographic resolution of (+)- and (-)-trans-2-Benzyl-cyclohexan-1,2-diamine Hydrochlorides
P. Bisel, M. Schlauch, E. Weckert, K.-S. Sin, A.W. Frahm
Chirality (2001) 13, 89-93
A thermodynamic study of the temperature-dependent elution order of cyclic
a-amino acids on a copper (II)-D-penicillamine chiral stationary phase
M. Schlauch, A.W. Frahm
Analytical Chem. (2001) 73, 262-266
Residue Mass Plot and Abundance Plot: Detection of Isobaric
Interferences in DE-MALDI-TOF-Mass Spectra of Complex Polymer Mixtures
Th. Meyer, D. Waidelich, M. Kunkel, A.W. Frahm
J. of the American Society, Mass Spectrom (2001) 12, 911 – 925
Asymmetric Synthesis and Chromatographic Resolution of
all Four Stereomers of the a,b-Propanoleucine
P. Bisel, E. Breitling, M. Schlauch, F.-J. Volk, A.W. Frahm
Pharmazie (2001) 56, 770 – 772
Enantiomeric and diastereomeric HPLC-separation of cyclic
b-substituted a-amino acids on a teicoplanin chiral stationary phase
M. Schlauch, A.W. Frahm
J. of Chromatography A (2000) 868, 197-207
Determination of the immunosuppressive drug mycophenolic acid
in serum with micellar elektrokinetic capillary chromatography (MECC)
S. Noé, J. Böhler, A.W. Frahm
J. of Pharm. and Bio Analysis (2000) 197 – 202
Phytochemical investigation of Aglaia rubiginosa (Hiern) Pannell
S. Weber, J. Puripattanavong, V. Brecht, A.W. Frahm
Journal of Natural Products (2000) 63, 636-642
EPC Syntheses and Structure-Activity Relationship of Hypoglycemic Semicyclic Amidines
S. Hartmann, S. Ulrich, C. Hupfer, and A.W. Frahm
J. Eur. Med. Chem. (2000) 35, 377 – 392
The Heliangolide Dihydrohirsutolide from Arctotis fastuosa and Dichloromethyldihydrohirsutolide
Ahmed A. Ali, Nasr A. El-Emary, Azza A. Khalifa, Franz-J. Volk , August W. Frahm
Planta Medica (2000) 66, 585 - 588
Carbocyclic a-amino acids: asymmetric Strecker synthesis of a series
of 2-alkylated 1-aminocyclopentanecarboxylic acids
J. Wede, F.-J. Volk, A.W. Frahm
Tetrahedron Asymmetry (2000) 11, 3231 - 3252
Enantiomeric and diastereomeric HPLC-separation of cyclic b-substituted a-amino acids on a copper (II)-D-penicillamine chiral stationary phase
M. Schlauch, F.-J. Volk, K.P. Fondekar, J. Wede, A.W. Frahm
J. of Chromatography A, 897 (2000) 145 - 152
Determination of Cremophor EL ® in plasma after sample
preparation with solid phase extraction and plasma protein precipitation
Th. Meyer, J. Böhler, A.W. Frahm
J. of Pharm. and Biomed Analysis (2000) 24, 495 – 506
Phytochemical investigation of Aglaia andamanica Hiern
J. Puripattanavong, S. Weber, V. Brecht, A.W. Frahm
Planta Medica (2000) 66, 740 - 745
1999-1990
On the E/Z Isomerism of Semicyclic Amidinium Salts
S. Hartmann, V. Brecht, A. W. Frahm
Magn Reson Chem (1999) 37, 69-72
Substituted Xanthones as Antimycobacterial Agents 3rd communication: QSAR-Investigations
K.-J. Schaper, M. Pickert, A.W. Frahm
Arch Pharm - Pharmaceutical and Medicinal Chemistry (1999) 332, 91-102
Carbocyclic a-Amino Acids: Asymmetric Synthesis of all Four
1-Amino-2-hydroxycyclohexanecarboxylic acids
K. Pai Fondekar, F.-J. Volk, A.W. Frahm
Tetrahedron: Asymmetry (1999) 10, 727-735
(1’R,2’R)-3[(cis-2’-Cyclohexylmethylcyclopentyl)imino]-
2-azabicyclo[2.2.2]octane hydrobromide, a Hypoglycemic Semicyclic Amidine
S. Hartmann, E. Weckert, A.W. Frahm
Acta Cryst. Section C (1999), C 55, 806-808
Cis-(1S,2R)-1-Amino-2-Methoxycyclohexanecarboxamide Hydrochlorid
K.Pai Fondekar, F.-J. Volk, E. Weckert, A.W. Frahm
Acta Cryst. (1999) C55, 1167-1170
Temperature induced inversion of elution order in the enantioseparation
of sotalol on a CBH 1 based chiral column
K. Fulde, A.W. Frahm
Journal of Chromatography A (1999) 858, 33-43
Titrimetric determination of Cremophor EL in aqueous solutions and biofluids
Part 2: Ruggedness of the method with respect to biofluids
M. Kunkel, T. Meyer, J. Böhler, E. Keller, A.W. Frahm
J. of Pharm. and Bio. Analysis (1999) 21, 911-922
Constituents of Veltheimia viridifolia -II.
Spirocyclic Nortriterpenes of the Bulbs
G. Amschler, A.W. Frahm, D. Müller-Doblies and U. Müller-Doblies
Phytochemistry (1998) 47, 429-436
Efficiency of haemoperfusion materials at removing the fungal toxin orellanine from human plasma
K. Fulde, J. Böhler, E. Keller, A.W. Frahm
Pharmazie (1998) 53, 58-59
Structure-Activity Relationship of Homochiral 7-Substituted 1-Aminoindanes as 5-HT-Agonists
D. Landsiedel-Maier, A.W. Frahm
Arch. Pharm. Pharm. Med. Chem. (1998) 331, 59-71
P2-purinoceptor antagonists: IV. Blockade of P2-receptor subtypes and ecto-nucleotidases by compounds related to reactive blue 2
F. Tuluc, R. Bültmann (correspondence), M. Glänzel, A.W. Frahm, K. Starke
Naunyn-Schmiedeberg’s Arch Pharmacol (1998) 357, 111-120
The absolute Configuration of cis-(aS,1S,2R)-2-Methyl- 1(a-methylbenzylamino)-cyclohexanecarboxamide
F.-J. Volk, G. Mattern, E. Weckert, A.W. Frahm
Acta Cryst. (1998) C54, 387-389
Diastereo- and Enantioselective Synthesis of (+)- and (-)-cis-2-Aminocyclobutanols P. Bisel, E. Breitling, A.W. Frahm
Eur. J. Org. Chem. (1998) 729-733
Titrimetrische Bestimmung von Cremophor EL aus wäßrigen Lösungen und
Biofluiden. Teil 1: Validierung des potentiometrischen Titrationsverfahrens.
M. Kunkel, J. Böhler, E. Keller, A.W. Frahm
Pharmazie (1998) 53, 314-21
Substituted Xanthones as Antimycobacterial Agents 1st communication: Synthesis and Assignment of 1H/13C NMR Chemical Shifts
M. Pickert, A.W. Frahm
Arch Pharm - Pharmaceutical and Medicinal Chemistry (1998) 331, 177-192
Substituted Xanthones as Antimycobacterial Agents 2nd communication: Antimycobacterial Activity
M. Pickert, K.-J. Schaper, A.W. Frahm
Arch Pharm - Pharmaceutical and Medicinal Chemistry (1998) 331, 193-197
Erratum: Substituted xanthones as antimycobacterial agents,
Part 2: Antimycobacterial activity
Pickert, M., Schaper, K.J., Frahm, A.W.
(Archiv der Pharmazie (1998) 331 (193))
(1998) Archiv der Pharmazie, 331 (6), Page 230
Synthesis and in vitro efficacy of transferrin conjugates
of the anticancer drug chlorambucil U. Beyer, T. Roth, P. Schumacher, A.W. Frahm, H.H. Fiebig, C. Unger, F. Kratz
J.Med. Chem. (1998) 41, 2701-2708
Improved Synthesis of (RS)-3-Oxocyclopentanecarboxylic Acid: Characterisation of the Intermediates
S.-Y. Sung, P. Bisel, A. W. Frahm
Pharmazie (1998) 53, 521-524
Alkaloids of the Flowers of Pancratium maritimum D. T. A. Youssef, A.W. Frahm
Planta Medica (1998) 64, 669-670
A Novel Approach to the Rare 4- and 5-Alkylindan-2-ols P. Bisel, A.W. Frahm
J. Chem. Research (S) (1998) 590-591
Determination of prednisolone in serum of transplant patients using solid-phase extraction and micellar electrokinetic chromatography
S. Noé, J. Böhler, E. Keller, A.W. Frahm
J. of Pharm. and Bio. Analysis (1998) 18, 471-476
Evaluation and optimisation of separation buffers for the determination of corticosteroids with micellar electrokinetic capillary chromatography (MECC)
S. Noé, J. Böhler, E. Keller, A.W. Frahm
J. of Pharm. and Bio. Analysis (1998) 18(4-5), 911-918
Diastereoselective a-Iminoamine Rearrangement:
Asymmetric Synthesis of (R)-(-)- and (S)-(+)-2-Benzyl-2-hydroxycyclohexanone
P. Bisel, G. Lauktien, E. Weckert, and A.W. Frahm
Tetrahedron: Asymmetry (1998) 9, 4027-4034
Cytotoxic glycosphingolipid from Murdannia loriformis (Hassk.)
Rolla Rao et Kammathy
W. Jiratchiariakul, H. Okabe, P. Moongkarndi, A.W. Frahm
Thai J. of Phytopharmacy (1998) 5, 10-20
Quantitative Structure-Activity Relationship (QSAR) Study of Polyhydroxy Xanthones
J. Ungwitayatorn, M. Pickert, A.W. Frahm
Pharmaceutica Acta Helvetiae (1997) 72, 23-29
Synthesis and Antimycobacterial Activity of Nitroxanthones
1. Communication: The Synthesis and DSC-Analysis
W. Ibrom, A.W. Frahm
Drug Res (1997) 47, 767-773
Synthesis and Antimycobacterial Activity of Nitroxanthones 2. Communication: The Antimycobacterial Activity
W. Ibrom, K.-J. Schaper, A.W. Frahm
Drug Res (1997) 47, 662-667
Kapillarelektrophoretische Methodenentwicklung zur Trennung von Cremophor EL
M. Kunkel, J. Böhler, E. Keller, A.W. Frahm
Pharmazie (1997) 52,109-121
Asymmetric Synthesis and Structure-Activity Relationship
of the Four Stereoisomers of the Antibiotic Amidinomycin
Part 2: Microbiological Testing
S.-Y. Sung, M. Kist, A.W. Frahm
Arch. Pharm. Pharm. Med. Chem. (1997) 330, 21-24
Synthesis of Maleimide Derivatives of the Anticancer Drugs 5-Fluorouracil and
5’-Deoxy-5-fluorouridine for the Preparation of Chemoimmunoconjugates
U. Beyer, P. Schumacher, C. Unger, A. W. Frahm, F. Kratz
Pharmazie (1997) 52, 480-482
Diastereo- and Enantioselective Synthesis of Dimethylcyclohexanamines via Asymmetric Reductive Amination
B. Speckenbach, P. Bisel, A.W. Frahm
Synthesis (1997) 1325 - 1330
Diastereo-and Enantioselective Synthesis of Cis-Configured
2-Oxygenated Cyclohexanamines by Asymmetric Reductive Amination
G. Lauktien, F.-J. Volk, A.W. Frahm
Tetrahedron: Asymmetry (1997) 8, 3457-3466
Blockade of P2X- and P2Y-purinoceptors by compounds related to reactive blue 2. F. Tuluc, R. Bültmann, A.W. Frahm, K. Starke
Naunyn-Schmiedebergs Arch Pharmacol (1997) 355:R35
Investigation of anticancer compounds from Murdannia loriformis
W.Jiratchariyakul,P. Moongkarndi,H. Okabe,A.W. Frahm
Proceeding of the first Indochina Conference on Pharmaceutical Sciences
(Pharma Indochina 1997) Pharmacy in Harmony.
Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
20-23 May, 1997: 171-192.
Reinvestigation of Amaryllis belladonna
O.R. Queckenberg, A.W. Frahm, D. Müller-Doblies, U. Müller-Doblies
Phytochemical analysis (1996) 7, 156-160
Circular Dichroism of C-7, C-6 trans-fused Guaianolides of Centaurea scoparia
Diaa Youssef, A.W. Frahm
Phytochemistry (1996) 41, 1107-1111
The Absolute Configuration of Chlorojanerin; a chlorine
containing guaianolide from Centaurea scoparia
G. Mattern, E. Weckert, D. Youssef, A.W. Frahm
Acta Cristallographica (1996) C52, 1791-1793
Asymmetric Synthesis and Structure Activity Relationship of the
Four Stereoisomers of the Antibiotic Amidinomycin.
S.-Y. Sung, A.W. Frahm
Archiv der Pharmazie (1996) 329, 291-300
Asymmetric Strecker Synthesis of All Four 1-Amino-2-methyl-cyclohexanecarboxylic Acids
F.-J. Volk, A.W. Frahm
Liebigs Ann Chem (1996) 1893-1903
Assignment of 1H and 13C-NMR Chemical Shifts for Nitroxanthones
W. Ibrom, A.W. Frahm
Magn Reson Chem (1996) 34, 937-944
Bestimmung von Corticosteroiden in Humanserum mit der micellaren
elektronischen Chromatographie und direkter Probeninjektion
S. Noé, J. Böhler, E. Keller, A.W. Frahm
Sci. Pharm. (1996) 64, 591-600
Constituents of Veltheimia viridifolia :I. Homoisoflavanones of the Bulbs
G. Amschler, A.W. Frahm, A. Hatzelmann, U. Kilian, D. Müller-Doblies, U. Müller-Doblies
Planta Medica (1996) 62, 534-539
A Steroidal Glucoside from Murdannia loriformis (Hassk.) Rolla Rao et Kammathy
W. Jiratchirariakul, H. Okabe, A.W. Frahm
Thai J. of Phytopharmacy (1996) 3, 31-39
Alkaloids from Brunsvigia gregaria
O.R. Queckenberg, A.W. Frahm, D. Müller-Doblies, U. Müller-Doblies
Planta medica (1995) 61, 581-582
Constituents of the Egyptian Centaurea scoparia Part III:
Phenolic Constituents of the Aerial Parts
Diaa Youssef, A.W. Frahm
Planta medica (1995) 61, 570-573
Supercritical Fluid Extraction - Schnelligkeit und Selektivität in der Naturstoffanalytik
O.R. Queckenberg, A.W.Frahm
Die Pharmazie (1994) 49, 159-166
Revised Assignment of 13C-NMR-Signals to Quarternary Carbons
of the Amaryllidaceae Alkaloid Lycorin
M. Spohn, V. Brecht, A.W. Frahm
Arch. Pharmaz (1994) 327, 123-24
Constituents of the Egyptian Centaurea Scoparius Sieb Part I: Chlorinated Guaianolides of the Aerial Parts
D. Youssef, A.W.Frahm
Planta Medica (1994) 60, 267-271
Constituents of the Egyptian Centaurea scoparius Sieb Part II: Guaianolides of the aerial parts
D. Youssef, A.W. Frahm
Planta Medica (1994) 60, 572-575
Chlorine-containing guaianolides from the aerial parts of Centaurea scoparius
Youssef, D., Frahm, A.W
(1993) Planta Medica, 59 (7 SUPPL.).
Biflavanoids from the heartwood of Garcinia schomburgkiana and their structural elucidation as atropisomers
Häfner, A., Frahm, A.W.
(1993) Planta Medica, 59 (7 SUPPL.).
Phytochemical investigation of Veltheimia viridifolia
Amschler, G., Müller-Doblies, D., Müller-Doblies, U., Frahm, A.W.
(1993) Planta Medica, 59 (7 SUPPL.).
Chromatographic and Spectroscopic Coupling Technique, a powerful Tool for the Screening of wild growing Amaryllidaceae.
O.R.Queckenberg, A.W. Frahm
J.P.C. (1993) 6, 55-61
Enantioselective Amidoamination: A New regiospecific strategy for
the synthesis of chiral cyclohexane-1,2-diamino-derivatives
(13. Mitt. der Reihe: Asymmetrisch reduktive Aminierung von Cycloalkanonen)
W.H. Schlichter, A.W.Frahm
Arch Pharmaz (1993) 326, 429-36
The Absolute Configuration of (+)-2-Benzyl-
2-[N-(a-phenylethyl)amino]cyclohexanone Hydrochloride
R. Platzbecker, G. Will, K. Hümmer, E. Weckert, G. Lauktien, A. W. Frahm
Acta Cryst. (1993) C49, 307-310
Novel, enantioselective Synthesis of vicinal Cyclohexanane-Diamines as Key-
intermediates for highly selective Opioid Kappa and Sigma Agonists
(12. Mitt. der Reihe: Asymmetrische reduktive Aminierung von Cycloalkanonen)
W.H. Schlichter, A.W. Frahm
Asymmetry (1992) 3, 329-32
Guaianolides from Venidium Fastuosum
A.A. Ali, N.A. El-Emary, A.A. Khalifa, A.W. Frahm
Phytochemistry (1992) 31, 2781-84
Structure establishment by 2D-NMR of the product obtained in the reaction of
MCPBA and Himachalol and revised 1H-NMR assignments for the Himachalol.
P.K. Agrawal, M. Schneider, A.W. Frahm
MRC (1992) 30, 1079-1083
Chemotaxonomic investigation of wild growing amaryllidaceae using multidimensional coupling techniques: Development of a screening method
Queckenberg, O., Frahm, A.W., Muller-Doblies, D., Muller-Doblies, U.
(1992) Planta Medica, 58 (7 SUPPL.), Pages A699-A700.
Asymmetrische reduktive Aminierung von Cycloalkanonen 11. Mitt.: Die Synthese optisch aktiver 2- subst. Cycloheptanamine
L.K. Liem, A.W. Frahm
Arch. Pharmaz. (1991) 324, 335-47
Ein allgemeiner Zugang zu cyclischen a-Ketolethern
Th.Erker, A.W. Frahm
Sci. Pharm. (1991) 59, 82
Quantitative Struktur-Wirkungsbeziehungen bei Polyhydroxy-xanthonen 2. Mitt.: Synthese mehrfach oxigenierter 2-Hydroxyxanthone
N.M.A. Mahfouz, H. Hambloch, N.M. Omar, A.W. Frahm
Arch. Pharmaz. 323, 162-169 (1990)
Asymmetrische reduktive Aminierung von Cycloalkanonen 10. Mitt.: Die EPC-Synthese von bicyclischen N-Heterocyclen
F. Omar, A.W. Frahm
Arch. Pharmaz. 323, 923-28 (1990)
Asymmetrische reduktive Aminierung von Cycloalkanonen 12. Mitt.: Absolute Konfiguration und optische Reinheit 2-substituierter Cycloheptanamine
L.K. Liem, A.W. Frahm
Scientia Pharmaceutica 58, 353-71 (1990)
An Investigation of Keto-enol Tautomerism in 2-Acetyl-1-Tetralone by 2D NMR Spectroscopy
P.K. Agrawal, R.S. Thakur, A.W. Frahm, M. Schneider
M.R. C 28, 931-3 (1990)
1989-1980
Asymmetrische reduktive Aminierung von Cycloalkanonen 7. Mitt.: Die asymmetrische Synthese von cis-1R, 2R-und cis 1S, 2S-2-Arylcyclohexanaminen
C.M. Nachtsheim, A.W. Frahm
Arch. Pharmaz. 322, 187-97 (1989)
Asymmetrische reduktive Aminierung von Cycloalkanonen 8. Mitt.: Die EPC-Synthese arylsubstituierter cis-4aR,10bR- und cis-4aS,10bS-Oktahydrophenanthridine
C.M. Nachtsheim A.W. Frahm
Arch. Pharmaz. 322, 199-206 (1989)
Asymmetrische reduktive Aminierung von Cycloalkanonen 9. Mitt.: Die asymmetrische Synthese GABA-verwandter cycloaliphatischer Aminosäuren
F. Omar, A. W. Frahm
Arch. Pharmaz. 322, 461-71 (1989)
Absolute Configuration of (-)-4-Bromo-N-cis-2’-phenylcycloheptylbenzamide
L.K. Liem, A.W. Frahm, A. Kirfel, G. Adwidijaja
Acta Crystallographica C 46, 1268-71 (1989)
Asymmetrische reduktive Aminierung von Cycloalkanonen 6. Mitt.: Die asymmetrische Synthese der cis-4R.8R-und cis-4 S.8S-Dekahydrochinoline
F. Omar, A.W. Frahm
Arch.Pharm. 321, 111-114 (1988)
The Differentiation of Distereomeric 2-substituted Cyclohexanamines
with three Chirality Centres by 13C-NMR-Spectroscopy
G. Knupp, A.W. Frahm
Magnetic Resonance in Organic Chemistry 26, 37-41 (1988)
Absolute Configuration of (-)-4-Bromo-N-(cis-2'-phenylcyclopentane) benzamide
W. Wiehl, A. Kirfel, A.W. Frahm
Acta Cristallographica C43, 83-85 (1987)
Zur Stereochemie der 3-Oxo-5-phenyl-1-cyclopentancarbonsäuren 9. Mitt.: Synthese kernfluorierter, stereomerer 3-Oxo-5-phenyl-1-cyclopentancarbonsäuren.
M. Beck, S. Jaunich, A.W. Frahm
Arch. Pharmaz. 319, 29-37 (1986)
Zur Stereochemie der 3-Oxo-5-phenyl-1-cyclopentancarbonsäuren 10. Mitt.: Versuche zum Existenzbeweis der t-2-Methyl-3-oxo-r-5-(4-fluorphenyl)-t-1-cyclopentan-carbonsäure
I. Körfer, A.W. Frahm
Arch. Pharmaz. 319, 465-468 (1986)
Zur Stereochemie der 3-Oxo-5-phenyl-1-cyclopentancarbonsäuren 11. Mitt.: Synthese der stereomeren 3-Oxo-5-(2,3,4-pyridlyl)-cyclopentancarbonsäuren
M. Beck, A.W. Frahm
Arch. Pharmaz. 319, 366-372 (1986)
Stereochemie substituierter Glutarsäuren 2. Mitt.: Synthese kernfluorierter, mehrfach substituierter Glutarsäuren
S. Jaunich, A.W. Frahm
Arch. Pharmaz. 319, 399-405 (1986)
Asymmetrische reduktive Aminierung von Cycloalkanonen 5. Mitt.: Synthese und absolute Konfiguration 2-substituierter Cyclopentanamine
W. Wiehl, A.W. Frahm
Chem. Ber. 119, 2668-77 (1986)
Optisch Aktive, diastereomerenreine Dimethylcyclohexanamine aus
handelsüblichen Gemischen diastereomerer Dimethylhexananole
B. Speckenbach, A.W. Frahm
Sci. Pharm. (1986) 54, 172
Asymmetrische reduktive Aminierung von Cycloalkanonen 3. Mitt.: Der Einfluß von Katalysator und Reduktionsmittel auf die Dia- und Enantioselektivität
G. Knupp, A.W. Frahm
Arch. Pharm. 318, 250-7 (1985)
Quantitative Structure-Activity-Relationships with the Tuberculostatic Activity of Polyhydoxy Xanthones and their 13-C-NMR-Chemical Shifts
H. Hambloch, B. Wiedemann, A.W. Frahm
Eur. J. Med. Chem. 20, 71-77 (1985)
Asymmetrische reduktive Aminierung von Cycloalkanonen 4. Mitt.: Synthese optisch aktiver trans-3-substituierter Cyclohexanamine
G. Knupp, A.W. Frahm
Arch. Pharm. 318, 535-42 (1985)
Zur Stereochemie der 3-Oxo-5-phenyl-1-cyclopentancarbonsäuren 6. Mitt.: Chemo-, Regio- und Stereoselektivität der Methylierung von ß-Cyclopentanoncarbonsäureestern.
I. Körfer, A.W. Frahm
Arch. Pharmaz. 318, 364-9 (1985)
Absolute Configuration of (-)-cis-2-Ethylcyclohexanamine-hydrochloride by X-Ray Crystallography
G. Knupp, A.W. Frahm, A. Kirfel, T. Fröhlich, G. Will
Acta Cristallographica C41, 468-470 (1985)
Synthesis and spectroscopic properties of cis-1.3.3a.8a-Tetrahydro-cyclopent(a)inen-2.8-dion
G. Knupp, H. Hambloch, A.W. Frahm
Arch. Pharmaz. 318, 918-22 (1985)
Stereochemie substituierter Glutarsäuren 1. Mitt.: (±) threo- und erythro-2-Methyl-3-phenyl-glutarsäuren
A.W. Frahm
Arch. Pharmaz. 318, 1009-15 (1985)
Zur Stereochemie der 3-Oxo-5-phenyl-1-cyclopentancarbonsäuren 7. Mitt.: Synthese kernfluorierter, stereomerer 5-Phenyl-dihydrosarkomycine, Teil 1
I. Körfer, A.W. Frahm
Arch. Pharmaz. 318, 1030-37 (1985)
Zur Stereochemie der 3-Oxo-5-phenyl-1-cyclopentancarbonsäuren 8. Mitt.: Synthese kernfluorierter, stereomerer 5-Phenyl-dihydrosarkomycine, Teil 2
I. Körfer, A.W. Frahm
Arch. Pharmaz. 318, 1131-34 (1985)
13-C-NMR-Spectra of Amaryllidaceae Alkaloids Part 1: Alkaloids with the Crinane Skeleton
A.W. Frahm, A.A. Ali, M.A. Ramadan
Org. Magn. Res. 23, 804-808 (1985)
Die asymmetrische, reduktive Aminierung von 2-substituierten Cyclohexanonen, 2. Mitt.: Synthese und absolute Konfiguration von 2-substituierten Cyclohexanaminen
G. Knupp, A.W. Frahm
Chem. Ber. 117, 2076-98 (1984)
Phytochemical Investigation of Hippeastrum vittatum Part IV: Stereochemistry of Pancracine, the first 5,11-methanomorphanthridine alkaloid from Hippeastrum-structure of "Hippagine"
A.A. Ali, M.K. Mesbah, A.W. Frahm
Planta Medica 50, 188-9 (1984)
Alkaloidal Constituents of Crinum Bulbispermum Part III: Structural Elucidation of Bulbispermine
A.A. Ali, M.A. Ramadan, A.W. Frahm
Planta medica 50, 424-7 (1984)
Relative Configuration of the Alkaloid Augustamine
A.A. Ali, H. Hambloch, A.W. Frahm
Phytochemistry 22, 283-7 (1983)
Three Isoflavonoids from Iris Germanica
A.A. Ali, N.A. El-Emary, M.A. Al-Moghazi, F.M. Darwish, A.W. Frahm
Phytochemistry 22, 2061-63 (1983)
Alkaloids of Crinum latifolium
S. Ghosal, K. Saini, A.W.Frahm
Phytochemistry 22, 2305-09 (1983)
Phytochemical Investigation of Dalbergia Parviflora II
Neoflavanoidal and Benzophenone Constituents.
N. Muangnoicharoen, A.W. Frahm
Phytochemistry 21, 767-772 (1982)
13-C-NMR-Spectroscopy of substituted Xanthones IV:
13-C-NMR-Spectral Study of Polyacetoxy Xanthones.
R.K. Chaudhuri, A.W. Frahm
Org. Magn. Res. 19, 12-4 (1982)
13-C-NMR-Spectroscopy of substituted Xanthones V:
Computer supported structure elucidation of Poly-Hydroxy-, Methoxy- and Acetoxy-Xanthones.
H. Hambloch, A.W. Frahm
Org. Magn. Res. 19, 43-8 (1982)
Zur Stereochemie der 3-Oxo-5-phenyl-cyclopentancarbonsäuren V:
Zur stereoselektiven Synthese der stereomeren 5-Phenyl-dihydroisosarkomycine
A.W. Frahm
Arch. Pharmaz. 315, 858-65 (1982)
New Arylbenzofurans from Dalbergia Parviflora
N. Muangnoicharoen, A.W. Frahm
Phytochemistry 20, 291-3 (1981)
The Alkaloids of Crinum Augustum Rox. I.
Two new nonhydroxylated Amaryllidaceae Alkaloids.
A.A. Ali, H. Kating, M.A. El-Moghazi, M.A. Ramadan, A.W. Frahm
Phytochemistry 20, 1121-3 (1981)
The Alkaloids of Crinum Augustum Rox. II. Four new 6-hydroxylated Alkaloids in the Crinine series
A.A. Ali, H. Kating, A.W. Frahm
Phytochemistry 20, 1731-3 (1981)
The Alkaloids of Crinum Augustum Rox. III. Augustine, a new 1,2-Epoxyalkaloid in the Crinine series;
the relative configuration.
A.A. Ali, H. Kating, A.W. Frahm
Phytochemistry 20, 1735-8 (1981)
Simple Synthesis of Methylsubstituted Cyclohexanamines
with high Stereoselectivity
G. Knupp, A.W. Frahm
J. Chem. Research 4, 164-5 (1981)
Asymmetric Synthesis of 2-Alkyl (Aryl)cyclohexanamines
G. Knupp, A.W. Frahm
Tetrahedron Letters 22, 2633-6 (1981)
Alkaloids of Crinum Pratense.
S. Ghosal, P.H. Rao, D.K. Jaiswal, Y. Kumar, A.W. Frahm
Phytochemistry 20, 2003-7 (1981)
Phytochemical Investigation of Hippeastrum vittatum Part III: Structural Elucidation of Hippadine
A.A. Ali, M.K. Mesbah, A.W. Frahm
Planta Medica 43, 407-9 (1981)
Ein neues Sesquiterpenketon aus Arnica-Arten
R. Schmitz, A.W. Frahm, H. Kating
Phytochemistry 19, 1477-80 (1980)
13-C-NMR-Spectrocopy of substituted Xanthones III:
Computer supported structure elucidation of Polyhydroxyxanthones
H. Hambloch, A.W. Frahm
Tetrahedron 36, 3273-3280 (1980)
Reserved Substituent Effect for the 13-C-NMR Chemical
Shifts in the unsubstituted Ring of para-substituted Benzophenones.
H. Hambloch, A.W. Frahm
Org. Magn. Res. 14, 444-6 (1980)
1979-1970
13-C-NMR-Spectroscopy of substituted Xanthones Part II:
13-C-NMR Spectral Study of Polyhydroxyxanthones
A.W. Frahm, R.K. Chaudhuri
Tetrahedron 35, 2035-8 (1979)
Prostalidins A,B,C and retrochinensin, new antidepressant
4-Aryl-2,3-naphthalide lignans from Justitia prostata
S. Ghosal, S. Baneryee, A.W. Frahm
Chemistry and Industry (London) 1979, 854-5
13-C-NMR-Spectroscopy of Polymethoxyxanthones
R.K. Chaudhuri, F. Zymalkowski, A.W. Frahm
Tetrahedron 34, 1837-40 (1978)
Zur Stereochemie der 3-Oxo-5-phenyl-1-cyclopentancarbonsäuren II: Die stereomeren 5-Phenyl-dihydroisosarkomycine
A.W. Frahm
Liebigs Ann. Chem. 1976, 600-609
Zur Stereochemie der 3-Oxo-5-phenyl-1-cyclopentancarbonsäuren, III:
Synthese der stereomeren 5-Phenyl-dihydro-sarkomycine; Teil 1
A.W. Frahm
Liebigs Ann. Chem. 1976, 824-834
Zur Stereochemie der 3-Oxo-5-phenyl-1-cyclopentancarbon-säuren IV: Synthese der stereomeren 5-Phenyl-dihydro-sarkomycine;Teil 2 A.W. Frahm
Liebigs Ann. Chem. 1976, 835-842
Die Synthese von ß-Phenyl-isoserinen durch Ammonolyse von
ß-Phenylglycidestern (II)
E. Kamandi, A.W. Frahm, F. Zymalkowski
Arch. Pharmaz. 308, 135-141 (1975)
Die Synthese von ß-Phenyl-isoserinen durch Ammonolyse von
ß-Phenylglycidestern (I)
E. Kamandi, A.W. Frahm, F. Zymalkowski
Arch. Pharmaz. 307, 871-8 (1974)
Die absolute Konfigration der 4 isomeren cis- und trans-
6-Amino-6,7,8,9-tetrahydro-5H-benzocycloheptenole-(5)
G. Mohr, A.W. Frahm, F. Zymalkowski
Liebigs Ann. Chem. 756, 103-111 (1972)
Darstellung und Acetolyse des 2,4-Dihydroxy-3-morpholino-methyl-acetophenons
H.E. Hagen, A.W. Frahm, R. Brandes, H.J. Roth
Arch. Pharmaz. 303, 988-993 (1970)
1969-1964
Zur Stereochemie der 2-Phenyl-1-carboxy-cyclopentanone-(4)
A.W. Frahm
Liebigs Ann. Chem. 728, 21-31 (1969)
Darstellung von a + ß -Laktoncarbonsäuren aus
D,L-3-(1'-Methoxymethylpropyl-)glutarsäure
A.W. Frahm
Arch. Pharmaz. 301, 621-623 (1968)
Die Synthese der D,L-3-(1'-Methoxymethylpropyl-)glutarsäure
F. Zymalkowski, A.W.Frahm
Naturwissenschaften 51, 57 (1964)
Syntheseversuche in der Emetinreihe
F. Zymalkowski, A.W. Frahm
Arch. Pharmaz. 297, 219-226 (1964)